Ventilation Mini Manual - Mode and Function Guide March 2015.pdf
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Dräger Ventilation Mini Manual
Brief explanation of ventilation modes and functions
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TABLE OF CONTENTS
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Table of contents
PC-BIPAP vs. PC-AC
Pressure Control – Biphasic Positive Airway Pressure vs.
Pressure Control – Assist Control
PC-APRV (Pressure Control – Airway Pressure Release Ventilation)
VC-MMV + AutoFlow
Volume Control – Mandatory Minute Volume + AutoFlow
ATC – Automatic Tube Compensation
SPN-PPS (Proportional Pressure Support)
SmartCare®
P0.1 – Occlusion Pressure Measurement
Leak Compensation
NIV (Non-invasive Ventilation)
Variable PS (Variable Pressure Support)
PEEPi (Intrinsic PEEP / AutoPEEP)
Low Flow Manoeuvre
Ventilation Terms
Notes
04 - 06
07 - 08
09 - 10
11 - 13
14 - 15
16 - 22
23 - 24
25 - 27
28 - 30
31 - 33
34 - 36
37 - 38
39 - 40
41 - 42
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PC-BIPAP VS. PC-AC
PC-BIPAP vs. PC-AC
Pressure Control – Biphasic Positive Airway
Pressure vs. Pressure Control – Assist Control
PC-BIPAP
PC-AC (BIPAP ASSIST)
–– machine- or patient-triggered, mechanical strokes with inspiratory
synchronisation
–– spontaneous breathing possible at any time
–– back-up frequency
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PC-BIPAP VS. PC-AC
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D-7523-2014
With PC-BIPAP the patient can breathe spontaneously at any time, while
the number of mandatory strokes is pre-set. In this mode, the mandatory
strokes exhibit both an inspiratory as well as expiratory synchronisation
with the patient’s breathing efforts. If the mandatory stroke is reduced
due to expiratory synchronisation, the subsequent mandatory stroke is
extended. The inspiratory synchronisation shortens the expiration phase.
In this case, the subsequent expiration time is extended by the missing
time. This ensures that the set mandatory breathing frequency (f)
remains constant. Machine-triggered mechanical breaths are applied if
no spontaneous breathing is detected during the inspiration trigger
window. The patient may receive Pressure Support (PS) during
spontaneous breathing at the PEEP level.
Fig. 1 (PC-BIPAP with mandatory and spontaneous mechanical breaths)
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PC-BIPAP VS. PC-AC
D-7529-2014
With PC-AC, every attempt to breathe that is detected on the PEEP
level triggers a mandatory mechanical breath. This means that the patient
determines the time and the number of mandatory mechanical breaths.
To give the patient enough time for expiration, it is not possible to trigger
another mandatory breath directly after a mechanical breath. A mandatory
breath is applied (backup frequency), if no mechanical breath has been
triggered after the expiratory time has elapsed.
Fig. 2 (PC-AC with triggered and untriggered mechanical breaths)
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PC-APRV
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PC-APRV
(Pressure Control – Airway Pressure Release Ventilation)
–– pressure-controlled
–– time cycled
–– machine-triggered
–– spontaneous breathing under continuous positive breathing pressure
with brief pressure relief times (screenshot)
In PC-APRV, the patient’s spontaneous breathing takes place at the
upper pressure level Phigh. This pressure level Phigh is maintained for the
duration of Thigh. To achieve active expiration, the pressure is reduced for
a brief period from Tlow to Plow. To support CO2 elimination, the pressure
is then reduced to Plow for the brief period Tlow. The alternation between
the two pressure levels is machine-triggered and time-cycled. The
breathing volume (VT) that expired during the relief times, results from
the pressure difference between Plow and Phigh and the lung mechanics.
If the resistance or compliance of the lungs changes during the
ventilation treatment, the supplied tidal volume (VT) and thus the minute
volume MV may also vary.
During the activation of AutoRelease, the duration of released pressure
is determined by the expiratory flow trace. The Exp. term. setting
determines the percentage by which the expiratory flow must fall short of
in relation to the peak flow for the ventilation to return to the high
pressure level.
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PC-APRV
D-7540-2014
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D-7539-2014
Fig. 1 (PC-APRV with AutoRelease on and measured Tlow in seconds)
Fig. 2 (PC-APRV with spontaneous breathing on Phigh level)
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VC-MMV + AUTOFLOW
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VC-MMV + AutoFlow
Volume Control – Mandatory Minute Volume + AutoFlow
–– volume-controlled ventilation to backup a mandatory minute volume
–– the mechanical breaths are automatically and gradually reduced for
patients with increasing spontaneous breathing, which is possible at
any time
–– enables automatic weaning by reducing the mechanical breathing
frequency and
–– necessary ventilation pressure
VC-MMV behaves in a similar manner to VC-SIMV; however, the
mandatory breaths are only administered if the spontaneous breathing is
insufficient and falls below a set minute volume. If the spontaneous
breathing increases, fewer mandatory breaths are administered. This
allows VC-MMV to ensure that the patient always at least receives the set
minimum volume MV (MV=VT*f). The applied mechanically triggered,
timed breaths are synchronised with the patient’s inspiratory efforts. This
ensures that spontaneous breathing is always possible for the patient at
the PEEP level. If the patient’s spontaneous breathing is sufficient to
achieve the set MV, no further mandatory breaths are applied. This
means that the set breathing frequency (f) is the maximum number of
mandatory breaths. The patient may receive Pressure Support (PS)
during spontaneous breathing at the PEEP level. Every inspiratory effort
by the patient at the PEEP level, which meets the trigger criteria, triggers
a pressure-supported mechanical breath. The time, number and duration
of the pressure-supported mechanical breaths are determined by the
patient’s spontaneous breathing.
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VC-MMV + AUTOFLOW
AutoFlow (AF) ensures that the set tidal volume (VT) is applied with the
minimum necessary pressure for all volume-controlled, mandatory
breaths. In the event of changing resistance (R) or compliance (C), the
pressure is gradually adjusted in order to administer the set VT. Both the
pressure and the flow are adapted automatically. The patient is able
to breath spontaneously during the entire breathing cycle, during
inspiration and expiration.
MV
Set MV
Mandatory MV
Spon. breathed MV
No
spontaneous
breathing
Starting
spontaneous
breathing
Sufficient
spontaneous
breathing
D-75-28-2014
Fig. 1 (from 100% ventilation to 100% spontaneous breathing)
Fig. 2 (VC-MMV + AF with mandatory breath and spontaneous breathing)
t
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ATC
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ATC
Automatic Tube Compensation
–– ensures that the set airway pressure is also obtained in the trachea
–– is calculated and displayed based on a mathematical tube model,
the set tube type and the tube’s internal diameter (tracheal pressure)
–– can be activated for any mode of ventilation
The tube as an artificial resistance in the airway is the main reason for
increased breathing effort by the patient. The automatic tube
compensation is a supplement for all ventilation modes and enables the
precise compensation of this increased work of breathing, with easy
setting options. The patient’s inspiratory effort should feel as if they are
not intubated. A gas flow through the tube leads to a pressure difference
(ΔP tube) between the start and end of the tube [Fig. 1]. This pressure
difference should stimulate the respiratory muscles in the form of
increased negative pressure in the lungs. However, the increased work
of breathing can be compensated by increasing the pressure in front of
the tube by precisely the amount of the pressure difference. This means
that the pressure in front of the tube also needs to be continuously
adapted to the relevant gas flow. The actual pressure difference is
calculated based on the gas flow measured by the ventilator. Automatic
tube compensation can be activated for any mode of ventilation. The tube
dimensions must first be set. The level of compensation (generally 100%)
can be used to fine-tune the settings for the relevant tube in order to
prevent overcompensation. The length of the tube does not have a
significant influence on the tube resistances, even for very short tubes,
and is not set.
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ATC
The tube compensation is applied for both inspiration as well as
expiration. [see Fig. 3] If necessary for expiratory compensation, the
pressure in the tube system is reduced to no less than the ambient
pressure in order to facilitate the patient’s exhalation. The control
ensures that the tracheal pressure does not fall below the set CPAP
pressure.
without ATC
with ATC
Paw
D-7480-2014
P trachea
P mus
Paw
P tube
P trachea
P tube
P mus
Fig. 1 Without ATC, the patient needs to apply the ΔP tube.
With ATC, the ventilator generates precisely this ΔP tube and provides relief for the
patient.
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ATC
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delta
P tube
25
Pressure difference between
the tube connector and the
tube tip for a 7.5 mm tube
20
15
10
PS undercompensation
D-7481-2014
5
PS overcompensation
10
20
PS pressure
30
40
50
60
70
Flow
80
Fig. 2 Set pressure support (PS) compared to pressure support required in principle (blue
line) for tube compensation.
Paw
Ptrach
Pressure at the Y-piece
Tracheal pressure
PEEP
Flow
t
t
Fig. 3 Pressure profile for tube compensation during inspiration and expiration.
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SPN-PPS
SPN-PPS
Spontaneous – Proportional Pressure Support
–– applies patient-triggered pressure support in proportion to the patient’s
inspiratory effort
–– the level of support can be set separately for restrictive or obstructive
work of breathing
For SPN-PPS, the pressure support should ideally be proportional to the
patient’s inspiratory effort. If the patient’s breathing is shallow, little
support is provided. More support is applied for a deep breath. The
absolute amount of support depends on both the Flow Assist and
Volume Assist parameter settings as well as the patient. The two types of
pressure support, pressure support proportional to volume (Volume
Assist) and pressure support proportional to flow (Flow Assist) [Fig. 1]
can be combined. If set correctly, only the illness-related higher work of
breathing is continuously adapted and compensated – the physiological
work of breathing continues to be provided by the patient alone. Flow
Assist helps overcome the resistance (R) and the pressure support is
proportional to the flow. In contrast, Volume Assist compensates the
elastic resistance (C) caused by reduced elasticity of the lungs. The
pressure support is proportional to the tidal volume. The relationship
between the inspiratory effort and the pressure support remains
constant for the same settings, while the pressure support varies for
every breath. If no spontaneous breathing is detected, the mechanical
support also ceases. Adequate apnoea and minute volume monitoring
must therefore be in place.
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SPN-PPS
Flow Assist: pressure profile proportional
to the flow
Vol. Assist: inspiration pressure profile
proportional to the tidal volume VT
Flow
Flow
VT
VT
t
t
Paw
t
Paw
PEEP
Inhalation
Exhalation
PEEP
t
D-7526-2014
Fig. 1 Rules for Flow and Volume Assist
Fig. 2 SPN-PPS, typical pressure and flow graph
Inhalation
Exhalation
t
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SMARTCARE®
SmartCare®
–– is an automatic clinical protocol
–– reduces the pressure support based on the averaged measured values
for the spontaneous respiratory rate, the tidal volume and the ETCO2
until the lowest possible level is reached
–– can reduce the overall ventilation period by up to 33% and the stay in
the intensive care unit by up to 20%1)
SmartCare®/PS is an automated clinical protocol, which was designed
to stabilise a patient’s spontaneous breathing in a “comfort zone” and
automatically reduce the respiratory support. The patient should be ready
for weaning, i.e. haemodynamically stable, and display adequate oxygenation and spontaneous breathing. SmartCare/PS attempts to keep the
patient within the “normal ventilation” range and places the patient back
“on the right track” in the event of a contrasting diagnosis. The patient’s
ventilation status is classified into eight different diagnoses and defined
measures are taken in order to bring the patient back to the “normal
ventilation” range, also referred to as the “respiratory comfort zone”. The
three key criteria are the spontaneous respiratory rate
(RRspon), tidal volume (VT) and endtidal CO2 (ETCO2) [ventilator’s
measured values]. This protocol is active during all phases of
a SmartCare/PS session. In addition, the pressure support level is
gradually reduced during the “adapt” phase, while continuous checks
confirm whether the patient is able to tolerate the new level. If this is the
case, the pressure support is reduced further, if not, it is increased back
to a level that is appropriate for the patient. The optimal case involves the
gradual and direct reduction of the pressure support until the lowest
level is reached.
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SMARTCARE®
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1) Lellouche, F. et al.; a Multicenter Randomized Trial of Computer-driven Protocolized Weaning from Mechanical
Ventilation. am J Respir Crit Care Med Vol 174. pp 894 -900, 2006 – The results are based on a randomised
study in several European hospitals with 144 patients who displayed a stable ventilation situation, a stable haemodynamic and neurological status and no ARDS prior to their initial weaning.
55 mmHg
Tachypnoe
Severe tachypnoea
Insufficient
ventilation
Hypoventilation
Normal
ventilation
Hyperventilation
20 mmHg
D-7482-2014
Unexplained
hyperventilation
ETCO2
35 bpm
30 bpm
15 bpm
fspn
Fig. 1 Diagnostics diagram based on the key criteria
Initiate
Adapt
Monitor
Maintain
No
Extubate?
Quickest path
D-7483-2014
Regression in case of permanent instabilities
Automatic protocol
User measures
Fig. 2 Functional principle – individual phases during SmartCare®
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SMARTCARE®
PREREQUISITES
It is important to choose the “right” patient. SmartCare/PS is ideal
for patients with primary restrictive problems and longer expected
weaning times. SmartCare/PS does not replace the clinician. The
advantage of SmartCare/PS is its ability to continuously monitor
the patient making appropriate changes to pressure support much
more often than this would be possible manually. Prior to starting
weaning with SmartCare/PS, the patient must be haemodynamically
stable, be ventilated with SPNCPAP/PS (optionally with ATC), and
the set PEEP must be ≤ 20 mbar.
QUICK START
1.PATIENT
a) Set the patient’s height; this
calculates the IBW and the
lower limit for the tidal volume
(Vt) can be derived from it.
b) Set the maximum permissible
PEEP value and the
inspiratory oxygen
concentration for the start of
the spontaneous breathing
test.
SmartCare/PS can be started with any PEEP setting between
0 and 20 mbar and with any selected FiO2 concentration. The
spontaneous breathing test starts once the target support pressure
(∆Psupp target, see 2.) has been reached and the PEEP and FiO2
values set by the user have been reached or undercut.
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SMARTCARE®
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2. A
CCESS TO THE AIRWAY
These settings define the target
support pressure at which the
spontaneous breathing test
starts (provided that PEEP and
FiO2 are also below the set
values – see 1). The following
table shows the dependencies
of the different settings:
Access to the airway,
type of humidification
ΔPsupp
target
IBW
Patient tracheostomised, active/no
humidification, ATC OFF
Patient endotracheally intubated, active/no
humidification, ATC OFF
Patient tracheostomised, HME filter,
ATC OFF
Patient endotracheally intubated, HME filter,
ATC OFF
Patient tracheostomised or endotracheally
intubated, active humidification, ATC ON
Patient tracheostimised or endotracheally
intubated, HME filter, ATC ON
5 mbar
≥ 36 kg
7 mbar
≥ 36 kg
9 mbar
≥ 36 kg
10 mbar
≥ 36 kg
0 mbar
≥ 36 kg
5 mbar
≥ 36 kg
If the therapists prefers to set target values for the pressure support
that differ from those that are shown in the table, he can enter
“wrong” specifications (e.g., tracheostomised rather than intubated)
to generate a different target value for the pressure support.
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SMARTCARE®
3. MEDICAL HISTORY
Selection of COPD and
neurological disorder for the
automatic adaptation of the
upper limit for etCO2 and the
respiratory rate (RR)
The COPD “Yes” setting means that the SmartCare/PS continues
to accept etCO2 values less than or equal to 64 mmHg (8.5Kpa) as
normal. This may also be helpful for patients with permissive
hypercapnia. The neurological disorder “Yes” setting means that the
SmartCare/PS continues to accept respiratory rates of up to 34/min
as normal. This may also be helpful for patients with higher
respiratory drive.
4. NIGHT’S REST
No active weaning takes place
during the selected period, i.e.,
SmartCare/PS maintains the
pressure support it had reached
prior to night rest commencing.
However, SmartCare/PS will
increase the pressure support if
the patients condition
deteriorates.
Night’s rest can also be set in order to give the patient a break
from weaning. It is also possible to set or switch off night’s rest
during an ongoing session.
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SMARTCARE®
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5. C HANGE THE GUIDELINE
Extended functionality for
customising the weaning
protocol.
This lets you define an individual respiratory comfort zone for the
patient. The set values of the medical history (see 3.) have no impact
if the guideline is changed.
6. START PATIENT SESSION
Flow measurement, CO2
measurement and apnoea
ventilation must be switched on.
The following icon appears in the header bar once the SmartCare/
PS session has successfully started
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SMARTCARE®
TIPS AND TRICKS
– Alarm limits must generally be set above and below the SmartCare/PS limit values (see instructions for use).
– An apnoea alarm leads to the unwanted cancellation of the
SmartCare/PS session.
Therefore, possible disconnections should be shorter than the
set apnoea time.
– A functioning CO2 measurement is required for SmartCare/PS
(position the CO2 cuvette to prevent the accumulation of
moisture or secretion, e.g., between the Y-piece and the HME
filter or vertically, pointing upward).
– Configure a specific SmartCare/PS view with the required
specific information (SmartCare/PS values, status and trends).
– Use the O2/suction function to perform a suction manoeuvre.
This pauses the SmartCare/PS and gives the patient time to
recover.
– The SmartCare/PS is suitable for adult and paediatric patients.
More information: www.draeger.com/smartcare
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P0.1 – OCCLUSION PRESSURE MEASUREMENT
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P0.1 – Occlusion Pressure Measurement
–– occlusion pressure measurement at the start of inspiration
–– is a measure of the neuromuscular respiratory drive1)
During a P0.1 manoeuvre, the ventilator closes the inspiratory valve for a
brief period after expiration and measures the airway pressure generated
over 100 ms by the inspiratory effort [Fig. 1]. The pressure is not
influenced by physiological compensation reactions, e.g. reflective
respiratory arrest or increased drive, within 100 ms. This pressure also
fundamentally depends on the muscular strength of the diaphragm. As a
result, the negative mouth pressure P0.1 after 0.1 seconds is a measure
of the neuromuscular respiratory drive1). The ventilator displays the value
of the measured pressure difference [Fig. 2]. For patients with healthy
lungs and calm breathing, the P.01 value is between 3 and 4 mbar (3 to
4 cmH2O). A higher P0.1 value reflects a high respiratory drive, which can
only be maintained for a limited time. P0.1 values over 6 mbar
(6 cmH2O), e.g. for a COPD patient, reflect imminent fatigue (respiratory
muscle fatigue). As shown in figure 1, the 100 ms starts once negative
pressure of -0.5 mbar (–0.5 cmH2O) is measured during the inspiratory
effort under PEEP/CPAP. The second pressure value is determined
after the 100 ms have elapsed. The inspiratory valve is simultaneously
opened. The patient can then breathe normally once again. The pressure
difference value “P2 - P1” defines the occlusion pressure P0.1.
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P0.1 – OCCLUSION PRESSURE MEASUREMENT
Normal value1):
P0.1 = 1 up to 4 mbar
P0.1 > 6 mbar, indication of imminent respiratory muscle fatigue,
high probability of weaning failure.
1) Oczenski W (ed). Atmen-Atemhilfen. 8. Auflage 2008
Tobin MJ (ed). Principles and Practice of Mechanical ventilation. Second Edition. McGraw-Hill, New York,
2006, Sasson CSH, et al. Airway Occlusion Pressure : An important Indicator for successful weaning in
patients with Chronic obstructive pulmonary disease. AM Respir Dis. 1987;135:107-113
Paw
PEEP
–0.5 mbar
(–0.5cm H2O)
Inspiratory valve
closed
100m s
Inspiratory valve open
t
P1
P0.1
P2
D-7524-2014
Fig. 1 Functional principle of the P0.1 measurement
Fig. 2 Screen layout during a P0.1 measurement
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LEAK COMPENSATION
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Leak Compensation
–– leaks are compensated for in volume- and pressure-controlled
ventilation
–– the inspiratory flow trigger threshold and the cancellation criteria for
pressure support are adapted automatically
–– leak compensation displays all the volume and flow measured values
with leak compensation
The ventilator determines the difference between the dosed inspiratory
flow and the flow measured during expiration. This difference defines the
size of the leak and is displayed as the leak minute volume MVleak and
the relative leak % (MVleak to MV). The leak correction calculation takes
the pressures in the breathing circuit into account. The percentage
volume loss during inspiration is greater than the loss during expiration,
as the pressure is higher during inspiration. The leak minute volume MVleak also considers inspiratory leaks. During volume-controlled
ventilation, the ventilator provides additional volume to compensate for
the leak. The ventilator compensates volume losses up to 100% of the set
tidal volume Vt. Measured volume and flow values are displayed with leak
compensation. An exception is the measured expiratory minute volume
as well as measured values marked as inspiratory or expiratory, such as
VTi and VTe. The inspiratory flow trigger threshold and the cancellation
criterion are applied to the leak-corrected flow, while both settings are
continuously adapted with respect to the leak.
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LEAK COMPENSATION
Vt
Tidal volume, leak-corrected
Vti
Inspiratory tidal volume, without leak-correction
Vte
Expiratory tidal volume, without leak-correction
Mv
Minute volume
Mvi
Inspiratory Minute volume, without leak-corrected
Mve
Expiratory Minute volume, total, without leak-corrected
Mvleak Leak Minute volume
(based on the medium pressure Paverage)