O P E R AT I N G & M A I N T E N A N C E M A N U A L
Single “E” Cylinder Yoke
Cylinder Pressure Gauge
N2O Pin Index Connector
Quick Connect to Yoke
Gas Exhaust Port
5 Foot Control Handle Assembly
Federal (USA) law restricts this
device to sale by or on the order
of a physician.
Trumbull, CT 06611
Phone: (203) 601-5200
Toll Free: (800) 243-2974
Fax: (800) 262-0105
The Frigitronics® CM-73 Cryosurgical System uses universally available medical
grade nitrous oxide in a completely non-electric instrument to provide temperatures
down to -890C. A selection of interchangeable screw-on probes is available for
procedures in gynecology, general surgery and otorhinolaryngology.
When the ON/OFF control valve is opened, N2O gas is supplied to the probe
causing rapid cooling via the Joule-Thomson principle. Activating the trigger on the
probe handle permits warm gas to be present in the probe for defrosting.
Probes and cylinders of nitrous oxide are quickly and easily changed. The unit
features low-pressure operation—except during defrost—for complete safety.
A specially designed safety feature prevents the use of high-pressure defrost gas
unless the probe is properly secured in the probe handle. The CM-73 Cryosurgical
System can be obtained with provisions for single or double cylinder operation.
Cylinder yokes are available to accommodate the 6.5 lb. ”E” cylinder, the 20 lb.
cylinder, and the 60 lb. ”G” cylinder (weights are gas content only). Other yokes to
fit cylinders manufactured outside the USA are available through our International
Department and/or Frigitronics dealer representatives.
The probes are of high-quality stainless steel, welded
construction. They are lightweight, slender and easy-tohandle. Available in a variety of configurations, all probes
thread securely into the probe handle and feature a knurled
finger grip for ease of installation.
Consisting of a comfortable handle with a trigger-type
defrost, the probe handle assembly is provided with a single
coaxial line that both supplies N2O to the probe and carries
away the exhaust gas. A quick-disconnect attaches the
probe line for easy installation.
Hand-tightening or a small wrench is all that is required
to attach the yoke to a cylinder of nitrous oxide. The key pin
index of the ”E” cylinder prevents the inadvertent use of any
other gas cylinder. Yokes are available for both single and
double cylinder operation. A pressure gauge indicates gas
pressure in the supply cylinder and a 90-degree ON/OFF
valve is used to start or stop gas flow to the probe.
A removable handle is provided to open and close the
N2O ”E” cylinder(s).
Single and double bottle carts are available for securing one
or two ”E” cylinders of N2O in a compact mobile carrier.
A single bottle cart is also available to accommodate a
20 lb. N2O cylinder.
An attractive attache case is compartmentalized to carry all
CM-73 components except the cylinders and bottle cart.
The built-in exhaust port is designed for the attachment of
tubing to safely vent nitrous oxide exhaust gases out of the
treatment area. Silicon tubing, 3/8” inner diameter X 1/16”
wall is recommended. All tubing should be routed overhead
to minimize the accidental restriction of the exhaust gases.
Use only the exhaust hose provided. Substitutes are not
recommended. DO NOT restrict or kink the exhaust hose
in any way.
1 Place the cylinders of medical grade nitrous oxide in the bottle cart.
Orientate the bottles so that the pin index (holes) in the valve face the pins on
the yoke with the pressure gauge facing forward.
2 Position the ”E” cylinder yoke to the cylinder valve. If a double cylinder yoke is
being used, set up both cylinders in the same manner. Be sure that the Teflon
washer supplied with each ”E” yoke is in place. Extra washers are provided in
the attache case. Place the yoke over the valve and insert the pins into the valve
for the ”E” yoke connection.
The 20 lb. cylinder yoke and the “G” cylinder yoke are identical. Attach the yoke
assembly to the gas cylinder.
3 Tighten the yoke "hand-tight" if using the ”E” yoke, and wrench-tight for the 20
lb. or ”G” cylinder.
4 Place the round cylinder handle on the ”E” cylinder valve.
Test cylinder pressure and yoke assembly by placing the
ON/OFF valve in the OFF position (the handle should be
turned 90O to the line) and opening the cylinder valve fully
with the handle provided. A reading between 740 and 800
psi should be indicated by the pressure gauge when
opening a full cylinder. Pressure is dependent on fullness of
cylinder and ambient temperature, but the system should
not be used if cylinder pressure is less than 600 psi.
At this time, any leaks should be audible. Replace Teflon
washer if necessary and tighten yoke.
NOTE: Cylinder should be kept at room temperature (72OF) for a minimum
of 2 hours to ensure pressure readings.
Probe Assembly Set-Up
Remove the probe handle assembly from the carrying case. A probe should be on the
probe handle at all times to protect the delivery tube from damage.
1 To remove a probe • Unscrew the probe using the knurled finger grip, turning
The probe must be slid straight forward until it clears the end of
the delivery tube.
2 To attach a probe • Select the probe that is desired for the procedure. Check
that an undamaged "O" ring is in place at the threaded end. Carefully place
the probe over the delivery tube and screw on securely (finger tight).
NOTE: Changing probes should be done with the the ON/OFF valve to "OFF".
To ensure that no gas is flowing through the probe, wait at least 10
seconds before removing tip.
3 Attach the probe line to the yoke assembly by placing the probe line male end
of the quick-disconnect into the female component on the yoke assembly.
Pull the collar back on the female fitting, insert the male fitting to the position
such that the collar will slip forward, and the male fitting will lock in place.
Pull gently to check that the probe line is secured.
4 To check probe operation/Freeze Test • With the cylinder valve open,
turn ON/OFF valve "ON" (handle parallel with line). The tip of the probe will
begin to freeze. Exhaust gas will be audible exiting the exhaust port near
5 To check probe operation/Defrost Test • Firmly depress the trigger on the
probe handle. Audible gas flow will stop.The tip of the probe will defrost quickly.
In some cases, when using probes with large freezing areas, it may be
necessary to momentarily release and then depress the trigger. This
supplies additional warm gas for defrost and may be repeated as
needed for complete defrost.
1 With the cylinder valve fully opened and the desired probe in position, turn
ON/OFF valve "ON".
2 Firmly depress the trigger on the probe handle to warm the end of the probe.
3 Apply the end of the probe to the tissue to be treated. Release the trigger to
freeze the tissue for the required length of time. An optional timer is available.
4 At the end of the freeze time, depress the trigger to warm the probe. Remove
the probe from the tissue after the tip has completely defrosted ( 00C on the
pyrometer). Larger probes, for more extensive freezing, require depressing the
trigger two or three times to accelerate the defrost mode.
5 Turn ON/OFF valve to "OFF" and prepare for next procedure.
1 With the ON/OFF valve to "OFF", the probe line can be removed, or the probe
can be replaced. The probe line can be disconnected by pushing back the
collar on the female part of the quick-disconnect and pulling the probe line
2 At the end of procedure—or the end of the day—shut off supply cylinder by
turning the cylinder valve clockwise.
The Frigitronics® CM-73 Cryosurgical System should be handled with the care
required of any quality instrument. Avoid dropping or mishandling the unit and
periodically inspect the lines, fittings, seals and probes for damage. A probe should
always be kept in place over the delivery tube for protection. Do not constrict, kink,
clamp, lay objects on, or otherwise damage or restrict the probe line. The line serves
as both supply and exhaust for the nitrous oxide.
CAUTION: Do not block the exhaust port located near the quick-disconnect. If the
line or exhaust is restricted the outer tube could fill with gas, expand
Gas purifiers (optional) are available through CooperSurgical for systems being
used in areas where medical grade or dehydrated nitrous oxide is not available.
Gas contaminants (water, oil, vapor or solid impurities) may cause blockage and
reduce operating efficiency.
Tips, handle and lines can be wiped clean with a mild disinfecting solution or alcohol
(70% isopropyl alcohol) presently used in the office or hospital. Cidex cold soaking
MUST NOT be utilized because it will attack the materials in the probe, and will
introduce excessive amounts of liquid.
Sterilization The Removable Probe Tips may be sterilized by:
2800F maximum temperature for a minimum of three minutes.
Extended exposure time is required with lower temperatures.
EO (ETHYLENE OXIDE) GAS
Temperature . . . . . . . . . . . . . . . .125-130°F
50% RH (pre-humidity) . . . . . . . . .60 minutes
. . . . . . . . . . . . . . . . . . . . . . .0/+10 minutes
Pre Vacuum . . . . . . . . . . . . .24” Hg ± 2” Hg
6-8 psig (550-660 mg/L EO)
Exposure Time . . . . . . . . . .4 hours minimum
Post Vacuum . . . . . . . . . .24” Hg 2X ± 2” Hg
Aeration . . . . . . . . . .12-0/+1 hours at 120°F
The particular EO cycle should be validated per the equipment
manufacturer’s requirements. It is recommended that each institution
employ procedures which include the use of biological indicators in
order to determine the effectiveness of the ethylene oxide process.
The Frigitronics® CM-73 Cryosurgical System probes may be sterilized by autoclaving, flash autoclaving or EO gas, or in accordance with the manufacturer's direction.
The probe MUST NOT BE immersed more than 6 inches (tip end only). DO NOT
sterilize handle, line, yoke assembly, etc.
WARNING: Do not immerse or soak the line or handle. Do not let the solution
reach probe handle, or enter internally.
1 It is recommended that nitrous oxide cylinders be at room temperature in order
to supply gas at the pressures desired. In some cases, cylinders stored
outdoors in cold weather will not produce sufficient gas pressure. They must
be warmed to room temperature for satisfactory operation.
2 Do not attempt to remove yoke assembly without first turning off the
3 Do not unscrew the probe or remove the probe line quick-disconnect without
first turning the ON/OFF valve to “OFF” and releasing the trigger on the probe
4 When the trigger valve is depressed and then released during operation,
an audible surge of gas will be heard. This is normal.
5 Prior to beginning a procedure, the probe should be at room temperature.
Depress the trigger to warm the tip before applying to tissue.
6 The probe line is supplied with a sintered metal filter located at the male part
of the quick-disconnect. Take care to keep the surface of this filter clean.
7 In the unlikely event of an uncontrolled freeze, simply turn the ON/OFF valve
to “OFF” and irrigate the probe tip until it defrosts.
8 In case of inadequate freeze or premature defrost, check the following:
• Low cylinder pressure/Replace cylinder.
• ON/OFF valve partially open/Open valve fully.
• Obstruction in line or delivery tube/Return to CooperSurgical for repair.
• Contamination in supply cylinder/Clean lines and replace supply cylinder.
• Leaks in fitting/Check washer and O-ring, tighten fittings.
• Purifier assembly
• Gas Filters
• “O”-Ring Filter
• Optional Timers
• "E" Cylinder Handles
• "E" Yoke Seals (2)
• 20 lb. "G" Yoke Seals (2)
• 20 foot Scavenger Tubing
• Probe Storage Clip
• Operating & Maintenance
CooperSurgical warranties The Frigitronics® CM-73 Cryosurgical System and
probes for a period of one year against defects in material and workmanship.
Frigitronics® is a registered trademark of CooperSurgical
Part #35651 • Revised 6/03
Trumbull, CT 06611
Phone: (203) 601-5200
Toll Free: (800) 243-2974
Fax: (800) 262-0105